8 | | (Tutaj będzie abstrakt, jak już się zdecydujemy na jego treść) |
| 8 | One of the challenges of modern neuroscience is integrating voluminous data of diferent |
| 9 | modalities derived from a variety of specimens. This task requires a common spatial framework |
| 10 | that can be provided by brain atlases. The first atlases were limited to two-dimentional presentation of structural data. Recently, attempts at creating 3D atlases have been made to offer navigation within non-standard anatomical planes and improve capability of localization of different types of data within the brain volume. |
| 11 | |
| 12 | The 3D atlases available so far have been created using frameworks which make it difficult for other |
| 13 | researchers to replicate the results. To facilitate reproducible |
| 14 | research and data sharing in the field we propose a SVG-based Common |
| 15 | Atlas Format (CAF) to store 2D atlas delineations or other compatible data |
| 16 | and ''3D Brain Atlas Reconstructor'' (3dBAR), software dedicated to automated |
| 17 | reconstruction of three-dimensional brain structures from 2D |
| 18 | atlas data. The basic functionality is provided by 1) a set of parsers |
| 19 | which translate various atlases from a number of formats into the CAF, |
| 20 | and 2) a module generating 3D models from CAF datasets. |
| 21 | |
| 22 | This methodology allows for the generation of 3D models in a |
| 23 | reproducible and configurable manner. The users of the software may |
| 24 | also track and review the whole reconstruction process in order to |
| 25 | find and correct errors. |
| 26 | Our workflow allows for manual corrections to be made when |
| 27 | automatic reconstruction is not sufficient. |
| 28 | |
| 29 | The software was designed to simplify interoperability with other |
| 30 | neuroinformatics tools by using open file formats (SVG, XML, VRML). |
| 31 | The content can easily be exchanged at any stage of data |
| 32 | processing. The framework allows for the addition of new public or |
| 33 | proprietary content. Most of the framework was implemented as a Python |
| 34 | module with an API. |